Thap3 Gene Summary [Mouse]
Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Is expressed in central nervous system and genitourinary system. Orthologous to human THAP3 (THAP domain containing 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Thap3 |
| Official Name | THAP domain containing, apoptosis associated protein 3 [Source:MGI Symbol;Acc:MGI:1917126] |
| Ensembl ID | ENSMUSG00000039759 |
| Bio databases IDs | |
| Aliases | THAP domain containing, apoptosis associated protein 3 |
| Synonyms | 2010013E08RIK, 2210418H06RIK, MGC33488, RGD1308109, THAP domain containing 3, THAP domain containing, apoptosis associated protein 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Thap3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- THAP domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Thap3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription from RNA polymerase II promoter
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding