Sdr9c7 Gene Summary [Mouse]

Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity. Predicted to be involved in retinol metabolic process and steroid metabolic process. Predicted to be located in cytoplasm. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Used to study autosomal recessive congenital ichthyosis 13. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 13. Orthologous to human SDR9C7 (short chain dehydrogenase/reductase family 9C member 7). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Sdr9c7
Official Name
4short chain dehydrogenase/reductase family 9C, member 7 [Source:MGI Symbol;Acc:MGI:1917311]
Ensembl ID
ENSMUSG00000040127
Bio databases IDs NCBI: 70061 Ensembl: ENSMUSG00000040127
Aliases 4short chain dehydrogenase/reductase family 9C, member 7
Synonyms 1810054F20Rik, 4short chain dehydrogenase/reductase family 9C, member 7, ARCI13, Orphan short chain dehydrogenase/reductase, Rdh20, RDHS, SDR-O, short chain dehydrogenase/reductase family 9C member 7, short chain dehydrogenase/reductase family 9C, member 7
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sdr9c7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Rossmann-fold NAD(P)(+)-binding proteins
  • sepiapterin reductase
  • retinol dehydrogenase
  • enzyme
  • Enoyl-(Acyl carrier protein) reductase
  • short chain dehydrogenase

Pathways

Biological processes and signaling networks where the Sdr9c7 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lamellar ichthyosis
  • Alzheimer disease
  • keratocystic odontogenic tumor
  • keratocystic odontogenic tumors
  • autosomal recessive congenital ichthyosis type 13
  • insomnia
  • headache
  • psoriasis
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sdr9c7 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • retinol metabolic process
  • steroid metabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • intracellular membrane-bounded organelle

Molecular Function

What the gene product does at the molecular level
  • retinol dehydrogenase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.