Rps19bp1 Gene Summary [Mouse]

Predicted to enable enzyme binding activity. Predicted to be involved in ribosomal small subunit biogenesis. Located in nucleolus and nucleoplasm. Is expressed in brain; male reproductive gland or organ; and metanephros. Orthologous to human RPS19BP1 (ribosomal protein S19 binding protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Rps19bp1
Official Name
ribosomal protein S19 binding protein 1 [Source:MGI Symbol;Acc:MGI:1913788]
Ensembl ID
ENSMUSG00000051518
Bio databases IDs NCBI: 66538 Ensembl: ENSMUSG00000051518
Aliases ribosomal protein S19 binding protein 1
Synonyms 2510038A11Rik, AROS, MGC52010, RGD1562823, ribosomal protein S19 binding protein 1, S19BP
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rps19bp1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • enzyme binding
  • protein binding
  • Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • neurotic disorder
regulates
  • TP53

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • pre-ribosome
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Rps19bp1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • ribosomal small subunit biogenesis

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • cytosol
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • enzyme binding

Gene-Specific Assays for Results You Can Trust

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