Pnrc1 Gene Summary [Mouse]
Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be active in P-body and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PNRC1 (proline rich nuclear receptor coactivator 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Pnrc1 |
| Official Name | proline-rich nuclear receptor coactivator 1 [Source:MGI Symbol;Acc:MGI:1917838] |
| Ensembl ID | ENSMUSG00000040128 |
| Bio databases IDs | |
| Aliases | proline-rich nuclear receptor coactivator 1 |
| Synonyms | 5730463C12Rik, B4-2, LOC102556064, PNAS-145, PNRC, PROL2, proline-rich nuclear receptor coactivator 1, PRR2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pnrc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Proline-rich nuclear receptor coactivator motif
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- breast cancer
- colorectal cancer
- plasma cell myeloma
- gastric cancer
- infection by HIV-1
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pnrc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasmic mRNA processing body
Molecular Function
What the gene product does at the molecular level
- protein binding