Wdr7 Gene Summary [Mouse]
Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in synaptic vesicle. Is expressed in nervous system; sensory organ; and testis. Orthologous to human WDR7 (WD repeat domain 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr7 |
| Official Name | WD repeat domain 7 [Source:MGI Symbol;Acc:MGI:1860197] |
| Ensembl ID | ENSMUSG00000040560 |
| Bio databases IDs | |
| Aliases | WD repeat domain 7 |
| Synonyms | AI462727, mKIAA0541, TRAG, Wd7, WD repeat domain 7 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Wdr7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- metabolic syndrome X
- glioblastoma
- glioblastoma cancer
- non-insulin-dependent diabetes mellitus
- heart septal defect
- Alzheimer disease
- alcoholism
- Tourette syndrome
role in cell
- differentiation
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- synaptic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Wdr7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- hemopoietic progenitor cell differentiation
Cellular Component
Where in the cell the gene product is active
- cytoplasm