Mfsd6 Gene Summary [Mouse]
Enables MHC class I protein binding activity and MHC class I receptor activity. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class I. Located in plasma membrane. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human MFSD6 (major facilitator superfamily domain containing 6). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfsd6 |
| Official Name | major facilitator superfamily domain containing 6 [Source:MGI Symbol;Acc:MGI:1922925] |
| Ensembl ID | ENSMUSG00000041439 |
| Bio databases IDs | |
| Aliases | major facilitator superfamily domain containing 6 |
| Synonyms | 2210010L05Rik, 9630025I22Rik, FLJ20160, hMMR2, major facilitator superfamily domain containing 6, MMR2, RGD1562317 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mfsd6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- MHC class I protein binding
- MFS_1 like family
- Major Facilitator Superfamily
- protein binding
- transmembrane receptor
- MHC class I receptor
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mfsd6 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- antigen processing and presentation of exogenous peptide antigen via MHC class I
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding