Tmem45b Gene Summary [Mouse]
Predicted to be involved in innate immune response. Predicted to be located in Golgi apparatus; endosome membrane; and lysosomal membrane. Is expressed in central nervous system; ganglia; gut; olfactory epithelium; and vibrissa. Orthologous to human TMEM45B (transmembrane protein 45B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem45b |
| Official Name | transmembrane protein 45b [Source:MGI Symbol;Acc:MGI:2384574] |
| Ensembl ID | ENSMUSG00000041737 |
| Bio databases IDs | |
| Aliases | transmembrane protein 45b |
| Synonyms | Loc120224, RGD1305586, transmembrane protein 45B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmem45b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Family of unknown function (DUF716)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmem45b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- innate immune response
Cellular Component
Where in the cell the gene product is active
- Golgi apparatus
- endosome membrane
- lysosomal membrane
Molecular Function
What the gene product does at the molecular level
- protein binding