Cds2 Gene Summary [Mouse]
Predicted to enable phosphatidate cytidylyltransferase activity. Involved in lipid droplet formation. Located in endoplasmic reticulum. Is expressed in several structures, including central nervous system; immune system; retina; skin; and testis. Orthologous to human CDS2 (CDP-diacylglycerol synthase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cds2 |
| Official Name | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 [Source:MGI Symbol;Acc:MGI:1332236] |
| Ensembl ID | ENSMUSG00000058793 |
| Bio databases IDs | |
| Aliases | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| Synonyms | 5730450N06Rik, 5730460C18Rik, CDP-diacylglycerol synthase 2, D2Wsu127e, LOC149832 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cds2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphatidate cytidylyltransferase
- enzyme
- protein binding
- Cytidylyltransferase family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetes mellitus
- heart failure
- idiopathic dilated cardiomyopathy
- systemic autoimmune syndrome
role in cell
- differentiation
- formation
- size
- maturation
- formation in
- partitioning in
- maturation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- cell cortex
- Endoplasmic Reticulum
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cds2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- CDP-diacylglycerol biosynthetic process
- phosphatidylglycerol biosynthetic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- phosphatidate cytidylyltransferase activity