Bpifa2 Gene Summary [Mouse]
Predicted to enable lipopolysaccharide binding activity. Predicted to be involved in defense response to bacterium. Located in extracellular space. Is expressed in central nervous system; major salivary gland; and retina. Orthologous to human BPIFA2 (BPI fold containing family A member 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bpifa2 |
| Official Name | BPI fold containing family A, member 2 [Source:MGI Symbol;Acc:MGI:97787] |
| Ensembl ID | ENSMUSG00000042459 |
| Bio databases IDs | |
| Aliases | BPI fold containing family A, member 2 |
| Synonyms | bA49G10.1, Bpifa2e, BPI fold containing family A member 2, BPI fold containing family A, member 2, C20orf70, PSP, SPLUNC2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bpifa2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- BPI
- lipopolysaccharide binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- secretory granules
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bpifa2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- defense response to bacterium
Cellular Component
Where in the cell the gene product is active
- extracellular space
- extracellular vesicular exosome
- secretory granule
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- lipopolysaccharide binding