Sdhaf3 Gene Summary [Mouse]
Predicted to be involved in mitochondrial respiratory chain complex II assembly and succinate metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrial intermembrane space. Orthologous to human SDHAF3 (succinate dehydrogenase complex assembly factor 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sdhaf3 |
| Official Name | succinate dehydrogenase complex assembly factor 3 [Source:MGI Symbol;Acc:MGI:1913288] |
| Ensembl ID | ENSMUSG00000042505 |
| Bio databases IDs | |
| Aliases | succinate dehydrogenase complex assembly factor 3 |
| Synonyms | 0610005M07Rik, 4933430A16RIK, ACN9, DC11, LRRGT00092, LYRM10, Sdh7, SDHF3, succinate dehydrogenase complex assembly factor 3 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sdhaf3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Complex 1 protein (LYR family)
- LYR (leucine-tyrosine-arginine) motif found in Complex1_LYR-like superfamily
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial intermembrane space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sdhaf3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex II assembly
- regulation of gluconeogenesis
- succinate metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrial matrix