Simc1 Gene Summary [Mouse]
Predicted to enable SUMO polymer binding activity and peptidase inhibitor activity. Predicted to be located in PML body and sarcomere. Orthologous to human SIMC1 (SUMO interacting motifs containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Simc1 |
| Official Name | SUMO-interacting motifs containing 1 [Source:MGI Symbol;Acc:MGI:2442599] |
| Ensembl ID | ENSMUSG00000043183 |
| Bio databases IDs | |
| Aliases | SUMO-interacting motifs containing 1 |
| Synonyms | 4732471D19Rik, C5orf25, OOMA1, PLEIAD, SUMO-interacting motifs containing 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Simc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protease inhibitor
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- sarcomere
- PML nuclear bodies
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Simc1 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- PML body
- cytoplasm
- sarcomere
Molecular Function
What the gene product does at the molecular level
- peptidase inhibitor activity
- protein binding
- SUMO polymer binding