Adam30 Gene Summary [Mouse]
Predicted to enable metalloendopeptidase activity. Predicted to be involved in male gonad development and proteolysis. Located in external side of plasma membrane and sperm head plasma membrane. Orthologous to human ADAM30 (ADAM metallopeptidase domain 30). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Adam30 |
| Official Name | a disintegrin and metallopeptidase domain 30 [Source:MGI Symbol;Acc:MGI:1918328] |
| Ensembl ID | ENSMUSG00000043468 |
| Bio databases IDs | |
| Aliases | a disintegrin and metallopeptidase domain 30 |
| Synonyms | 4933424D07RIK, ADAM metallopeptidase domain 30, a disintegrin and metallopeptidase domain 30, LOC683066, svph4 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Adam30 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Reprolysin family propeptide
- metallopeptidase
- ZnMc
- zinc ion binding
- ADAM cysteine-rich
- Metallo-peptidase family M12B Reprolysin-like
- peptidase
- Disintegrin
- Reprolysin (M12B) family zinc metalloprotease
Pathways
Biological processes and signaling networks where the Adam30 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- plasma membrane extracellular face
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Adam30 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- male gonad development
- proteolysis
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- membrane
- external side of plasma membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- zinc ion binding
- metalloendopeptidase activity
- metallopeptidase activity