Tor4a Gene Summary [Mouse]

Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be located in several cellular components, including cytoplasm; endomembrane system; and intracellular membrane-bounded organelle. Predicted to be active in endoplasmic reticulum lumen and nuclear envelope. Orthologous to human TOR4A (torsin family 4 member A). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tor4a
Official Name
torsin family 4, member A [Source:MGI Symbol;Acc:MGI:2442720]
Ensembl ID
ENSMUSG00000059555
Bio databases IDs NCBI: 227612 Ensembl: ENSMUSG00000059555
Aliases torsin family 4, member A
Synonyms A830007P12Rik, C9orf167, FLJ20245, RGD1308019, torsin family 4 member A, torsin family 4, member A
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tor4a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Torsin
  • AAA ATPase domain
  • P-loop containing Nucleoside Triphosphate Hydrolases
  • AAA domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • aortic valve calcification
  • metastatic colorectal cancer

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • alpha granules

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tor4a gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • platelet alpha granule lumen
  • nuclear envelope
  • endoplasmic reticulum lumen
  • membrane
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding

Gene-Specific Assays for Results You Can Trust

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