Mrpl50 Gene Summary [Mouse]

Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL50 (mitochondrial ribosomal protein L50). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl50
Official Name
mitochondrial ribosomal protein L50 [Source:MGI Symbol;Acc:MGI:107329]
Ensembl ID
ENSMUSG00000044018
Bio databases IDs NCBI: 28028 Ensembl: ENSMUSG00000044018
Aliases mitochondrial ribosomal protein L50
Synonyms D4Wsu125e, mitochondrial ribosomal protein L50, mL50
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl50 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal subunit 39S

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin resistance
regulated by
  • ACHE
  • sulforafan
  • SAMMSON

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Mitochondria
  • cytosol
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl50 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • cytosol
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.