Mrpl20 Gene Summary [Mouse]
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including extraembryonic component; ganglia; genitourinary system; jaw; and musculoskeletal system. Orthologous to human MRPL20 (mitochondrial ribosomal protein L20). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Processed Transcript |
| Official Symbol | Mrpl20 |
| Official Name | mitochondrial ribosomal protein L20 [Source:MGI Symbol;Acc:MGI:2137221] |
| Ensembl ID | ENSMUSG00000029066 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein L20 |
| Synonyms | 2610008D01Rik, 4930425I20Rik, bL20m, FLJ10024, L20mt, LOC642393, LOC687253, mitochondrial ribosomal protein L20 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrpl20 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- Ribosomal protein L20
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetes mellitus
- central nervous system cancer
- neoplastic cell transformation
- abdominal aortic aneurysm
- primary central nervous system lymphoma
- primary cancer
- lymphomagenesis
role in cell
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrpl20 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial ribosome
- mitochondrial large ribosomal subunit
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome
- rRNA binding