Bmerb1 Gene Summary [Mouse]
Acts upstream of or within negative regulation of cell motility involved in cerebral cortex radial glia guided migration and negative regulation of microtubule depolymerization. Located in microtubule cytoskeleton. Is expressed in several structures, including central nervous system; colon; cornea stroma; glans of male genital tubercle; and peripheral nervous system ganglion. Orthologous to human BMERB1 (bMERB domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Bmerb1 |
| Official Name | bMERB domain containing 1 [Source:MGI Symbol;Acc:MGI:1914504] |
| Ensembl ID | ENSMUSG00000044117 |
| Bio databases IDs | |
| Aliases | bMERB domain containing 1 |
| Synonyms | 2900011O08Rik, bMERB domain containing 1, C16orf45, MINP, RGD1305733 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Bmerb1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- microtubule cytoskeleton
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Bmerb1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell motility involved in cerebral cortex radial glia guided migration
- negative regulation of microtubule depolymerization
- negative regulation of cell motility involved in cerebral cortex radial glia guided migration
- microtubule depolymerization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
Molecular Function
What the gene product does at the molecular level
- protein binding