Dipk2a Gene Summary [Mouse]
Acts upstream of or within negative regulation of smooth muscle cell apoptotic process. Located in COPI-coated vesicle and extracellular region. Is expressed in several structures, including cerebral cortex; embryo mesenchyme; hair follicle; jaw; and musculoskeletal system. Orthologous to human DIPK2A (divergent protein kinase domain 2A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dipk2a |
| Official Name | divergent protein kinase domain 2A [Source:MGI Symbol;Acc:MGI:1916111] |
| Ensembl ID | ENSMUSG00000045414 |
| Bio databases IDs | |
| Aliases | divergent protein kinase domain 2A |
| Synonyms | 1190002N15Rik, Ab2-095, C3orf58, DIA1, divergent protein kinase domain 2A, GoPro49, HASF, RGD1309079 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Dipk2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein-kinase domain of FAM69
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Extracellular Space
- Golgi Apparatus
- Golgi membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Dipk2a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein kinase B signaling cascade
- negative regulation of smooth muscle cell apoptotic process
- positive regulation of protein kinase C activity
- cardiac muscle cell proliferation
Cellular Component
Where in the cell the gene product is active
- extracellular space
- Golgi membrane
- COPI vesicle coat