Stard5 Gene Summary [Mouse]
Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to be involved in cholesterol import. Is expressed in embryo; liver; metanephros; and small intestine. Orthologous to human STARD5 (StAR related lipid transfer domain containing 5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Stard5 |
| Official Name | StAR-related lipid transfer (START) domain containing 5 [Source:MGI Symbol;Acc:MGI:2156765] |
| Ensembl ID | ENSMUSG00000046027 |
| Bio databases IDs | |
| Aliases | StAR-related lipid transfer (START) domain containing 5 |
| Synonyms | 2310058G22Rik, D7Ertd152e, MGC10327, RGD1561783, StAR-related lipid transfer domain containing 5 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Stard5 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SRPBCC domain
- lipid transporter
- cholesterol binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
- cholesterol
- PRNP
disease
- epithelial cancer
- hepatocellular carcinoma
- liver cancer
- organismal death
- lung adenocarcinoma
- lung adenocarcinoma formation
- hepatitis B virus-related hepatocellular carcinoma
role in cell
- expression in
- migration
- fluidity
- invasion by
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
- Golgi Apparatus
- cytosol
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Stard5 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cholesterol import
Cellular Component
Where in the cell the gene product is active
- cytosol
Molecular Function
What the gene product does at the molecular level
- cholesterol binding