Krt32 Gene Summary [Mouse]

Predicted to enable structural molecule activity. Predicted to be involved in epithelial cell differentiation and intermediate filament organization. Predicted to be located in intermediate filament. Predicted to be active in cytoskeleton. Is expressed in esophagus; jaw bone; lung; skin; and urethra. Orthologous to human KRT32 (keratin 32). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Processed Transcript
Official Symbol
Krt32
Official Name
keratin 32 [Source:MGI Symbol;Acc:MGI:1309995]
Ensembl ID
ENSMUSG00000046095
Bio databases IDs NCBI: 16670 Ensembl: ENSMUSG00000046095
Aliases keratin 32
Synonyms HA2, Ha3, hHa2, HKA2, K32, Ka26, keratin 32, Krt1-2, KRTHA2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Krt32 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Phage minor structural protein GP20
  • Uso1 / p115 like vesicle tethering protein, C terminal region
  • Keratin, high sulfur B2 protein
  • protein binding
  • Intermediate filament protein
  • Apolipoprotein A1/A4/E domain

Pathways

Biological processes and signaling networks where the Krt32 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
  • male pattern hair loss
  • chronic lymphocytic leukemia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Krt32 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • epithelial cell differentiation
  • epidermis development
  • intermediate filament organization

Cellular Component

Where in the cell the gene product is active
  • cytoskeleton
  • extracellular vesicular exosome
  • cytosol
  • intermediate filament

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • structural molecule activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.