Ppp1r3b Gene Summary [Mouse]
Predicted to enable several functions, including [phosphorylase] phosphatase activity; glycogen binding activity; and protein phosphatase 1 binding activity. Predicted to contribute to phosphoprotein phosphatase activity. Involved in positive regulation of glycogen biosynthetic process. Predicted to be located in glycogen granule. Predicted to be part of protein phosphatase type 1 complex. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; respiratory system; and sensory organ. Orthologous to human PPP1R3B (protein phosphatase 1 regulatory subunit 3B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ppp1r3b |
| Official Name | protein phosphatase 1, regulatory subunit 3B [Source:MGI Symbol;Acc:MGI:2177268] |
| Ensembl ID | ENSMUSG00000046794 |
| Bio databases IDs | |
| Aliases | protein phosphatase 1, regulatory subunit 3B |
| Synonyms | 6430576E21, GL, LOC192280, LOC286044, PPP1R4, protein phosphatase 1 regulatory subunit 3B, protein phosphatase 1, regulatory subunit 3B, PTG |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ppp1r3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Starch/carbohydrate-binding module (family 53)
- Carbohydrate/starch-binding module (family 21)
- protein phosphatase
- phosphatase
- protein phosphatase regulator
- enzyme binding
- protein binding
- [phosphorylase] phosphatase
- PBD_PPP1R3
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- Alzheimer disease
- epithelial cancer
- diabetic nephropathy
- chronic obstructive pulmonary disease
- hepatocellular carcinoma
- liver cancer
regulates
- glycogen
- D-glucose
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ppp1r3b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycogen metabolic process
- regulation of glycogen biosynthetic process
- regulation of glycogen catabolic process
Cellular Component
Where in the cell the gene product is active
- protein phosphatase type 1 complex
- glycogen granule
Molecular Function
What the gene product does at the molecular level
- protein binding
- [phosphorylase] phosphatase activity
- protein phosphatase 1 binding
- glycogen binding
- protein phosphatase regulator activity