Nipsnap2 Gene Summary [Mouse]
Predicted to enable protein-macromolecule adaptor activity. Involved in mitophagy and positive regulation of high voltage-gated calcium channel activity. Located in cytoplasm. Is expressed in olfactory cortex ventricular layer; rest of cerebellum ventricular layer; and telencephalon ventricular layer. Orthologous to human NIPSNAP2 (nipsnap homolog 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nipsnap2 |
| Official Name | nipsnap homolog 2 [Source:MGI Symbol;Acc:MGI:1278343] |
| Ensembl ID | ENSMUSG00000029432 |
| Bio databases IDs | |
| Aliases | nipsnap homolog 2 |
| Synonyms | AV006093, GBAS, LOC498174, nipsnap homolog 2 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nipsnap2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding activity, bridging
- protein binding
- NIPSNAP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- Mitochondria
- cytosol
- mitochondrial matrix
- mitochondrial outer membrane
- synaptosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nipsnap2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oxidative phosphorylation
- macromitophagy
- mitochondrion organization
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
- mitochondrial outer membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein binding, bridging