Taf5l Gene Summary [Mouse]
Predicted to enable transcription coactivator activity. Involved in regulation of DNA-templated transcription and regulation of somatic stem cell population maintenance. Located in nucleus. Is expressed in genitourinary system and tail. Orthologous to human TAF5L (TATA-box binding protein associated factor 5 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Taf5l |
| Official Name | TATA-box binding protein associated factor 5 like [Source:MGI Symbol;Acc:MGI:1919039] |
| Ensembl ID | ENSMUSG00000038697 |
| Bio databases IDs | |
| Aliases | TATA-box binding protein associated factor 5 like |
| Synonyms | 1110005N04Rik, PAF65B, Taf5l1, TATA-box binding protein associated factor 5 like, TATA-box binding protein associated factor 5 like 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Taf5l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Anaphase-promoting complex subunit 4 WD40 domain
- TAF5 N-terminal domain 2
- transcription regulator
- transcription co-activator
- WD40 repeats
- WD domain, G-beta repeat
- WD40
- protein binding
Pathways
Biological processes and signaling networks where the Taf5l gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytoplasmic ribonucleoprotein granule
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Taf5l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of transcription, DNA-dependent
- regulation of DNA repair
- regulation of RNA splicing
- regulation of transcription, DNA-dependent
- transcription from RNA polymerase II promoter
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- transcription factor TFIID complex
- transcription factor TFTC complex
- nuclear speck
- SAGA complex
- histone acetyltransferase complex
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity