Tspyl1 Gene Summary [Mouse]
Predicted to enable chromatin binding activity; enzyme binding activity; and histone binding activity. Predicted to be involved in nucleosome assembly. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in gonadal dysgenesis and sudden infant death syndrome. Orthologous to several human genes including TSPYL1 (TSPY like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tspyl1 |
| Official Name | testis-specific protein, Y-encoded-like 1 [Source:MGI Symbol;Acc:MGI:1298395] |
| Ensembl ID | ENSMUSG00000047514 |
| Bio databases IDs | |
| Aliases | testis-specific protein, Y-encoded-like 1 |
| Synonyms | Al8, DKFZP564D152, testis-specific protein, Y-encoded-like 1, TSPYL, TSPY-like 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tspyl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleosome assembly protein (NAP)
- PTZ00007
- enzyme binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Tspyl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
- chromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone binding
- chromatin binding
- enzyme binding