TSPYL1 Gene Summary [Human]
The protein encoded by this gene is found in the nucleolus and is similar to that of a family of genes on the Y-chromosome. This gene is intronless. Defects in this gene are a cause of sudden infant death with dysgenesis of the testes syndrome (SIDDT). [provided by RefSeq, Dec 2009]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | TSPYL1 |
| Official Name | TSPY like 1 [Source:HGNC Symbol;Acc:HGNC:12382] |
| Ensembl ID | ENSG00000189241 |
| Bio databases IDs | |
| Aliases | TSPY like 1 |
| Synonyms | Al8, DKFZP564D152, testis-specific protein, Y-encoded-like 1, TSPYL, TSPY-like 1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TSPYL1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Nucleosome assembly protein (NAP)
- PTZ00007
- enzyme binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human TSPYL1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nucleosome assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
- chromatin
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- histone binding
- chromatin binding
- enzyme binding