Rnf150 Gene Summary [Mouse]
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in cranial ganglion; dorsal root ganglion; medulla oblongata basal plate mantle layer; and spinal cord mantle layer. Orthologous to human RNF150 (ring finger protein 150). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rnf150 |
| Official Name | ring finger protein 150 [Source:MGI Symbol;Acc:MGI:2443860] |
| Ensembl ID | ENSMUSG00000047747 |
| Bio databases IDs | |
| Aliases | ring finger protein 150 |
| Synonyms | A630007N06RIK, C030044C12RIK, Greul5, mKIAA1214, RGD1304572, ring finger protein 150 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rnf150 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PA domain
- RING-type zinc-finger
- PA
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- peptidase
- Ring finger domain
- protein binding
- RING-like zinc finger
- RING-H2 zinc finger domain
- Zinc finger, C3HC4 type (RING finger)
- zinc-RING finger domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- renal clear cell adenocarcinoma
- renal clear cell cancer
- multiple system atrophy
- endometrial carcinoma
- epithelial endometrial cancer
- conduct disorder
- HER2 negative hormone receptor negative breast cancer
- idiopathic scoliosis
- chronic obstructive pulmonary disease
- refractive error
role in cell
- replication in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rnf150 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- ubiquitin-dependent protein catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
Molecular Function
What the gene product does at the molecular level
- metal ion binding