Rell1 Gene Summary [Mouse]
Predicted to be involved in positive regulation of p38MAPK cascade. Predicted to be located in microtubule cytoskeleton. Predicted to be active in plasma membrane. Is expressed in retina. Orthologous to human RELL1 (RELT like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rell1 |
| Official Name | RELT-like 1 [Source:MGI Symbol;Acc:MGI:2140767] |
| Ensembl ID | ENSMUSG00000047881 |
| Bio databases IDs | |
| Aliases | RELT-like 1 |
| Synonyms | LOC253981, RELT-like 1, RGD1307468 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rell1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Tumour necrosis factor receptor superfamily member 19
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- idiopathic scoliosis
- colorectal adenoma
- colorectal adenoma formation
regulated by
- Mrc 5 cells
- KMT2D
- levodopa
- HUVEC cells
- lymphatic endothelial cells
- Akata cells
role in cell
- expression in
- apoptosis
- G2 phase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- microtubule cytoskeleton
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rell1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of p38MAPK cascade
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding