Ogfr Gene Summary [Mouse]

Predicted to enable opioid growth factor receptor activity. Predicted to be located in cytoplasm; membrane; and nucleus. Is expressed in genitourinary system and metanephros. Orthologous to human OGFR (opioid growth factor receptor). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ogfr
Official Name
opioid growth factor receptor [Source:MGI Symbol;Acc:MGI:1919325]
Ensembl ID
ENSMUSG00000049401
Bio databases IDs NCBI: 72075 Ensembl: ENSMUSG00000049401
Aliases opioid growth factor receptor
Synonyms 2010013E17Rik, 7-60, opioid growth factor receptor
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ogfr often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Domain of unknown function (DUF4573)
  • Kruppel-like factor (KLF) 9, KLF13, KLF14, KLF16, and similar proteins
  • Opioid growth factor receptor (OGFr) conserved region
  • protein binding

Pathways

Biological processes and signaling networks where the Ogfr gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • endometriosis
regulated by
  • heat-killed candida albicans
  • MAPK1
  • ETV3
  • L-methionine
  • F3
  • TNF (family)
  • CSF1
  • IL4
  • Influenza A virus (A/Alaska/6/1977(H3N2))
  • IFNG
role in cell
  • apoptosis
  • growth

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • Cytoplasm
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ogfr gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of cell growth

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.