Prss33 Gene Summary [Mouse]

Enables serine-type peptidase activity. Predicted to be involved in protein kinase C signaling and proteolysis. Located in extracellular space. Is expressed in several structures, including brain; musculature; reproductive system; sensory organ; and spleen. Orthologous to human PRSS33 (serine protease 33). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Prss33
Official Name
protease, serine 33 [Source:MGI Symbol;Acc:MGI:2661234]
Ensembl ID
ENSMUSG00000049620
Bio databases IDs NCBI: 353130 Ensembl: ENSMUSG00000049620
Aliases protease, serine 33
Synonyms EOS, mT6, serine protease 33, tryptase-6
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Prss33 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • serine endopeptidase
  • serine-type peptidase
  • peptidase
  • Domain of unknown function (DUF1986)

Pathways

Biological processes and signaling networks where the Prss33 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chronic periodontal disease
regulated by
  • dexamethasone
  • filgrastim
  • ALOX5

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Prss33 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein kinase C signaling cascade
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • cytoplasm

Molecular Function

What the gene product does at the molecular level
  • serine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

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