Sac3d1 Gene Summary [Mouse]

Acts upstream of or within microtubule cytoskeleton organization; negative regulation of receptor signaling pathway via JAK-STAT; and regulation of immune response. Located in centrosome; nucleus; and spindle. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SAC3D1 (SAC3 domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sac3d1
Official Name
SAC3 domain containing 1 [Source:MGI Symbol;Acc:MGI:1913656]
Ensembl ID
ENSMUSG00000024790
Bio databases IDs NCBI: 66406 Ensembl: ENSMUSG00000024790
Aliases SAC3 domain containing 1
Synonyms 2410004C24Rik, HSU79266, RGD1308049, SAC3 domain containing 1, SHD1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sac3d1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • SAC3/GANP family
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hyperplasia
regulated by
regulates
role in cell
  • proliferation
  • formation
  • assembly
  • number
  • function
  • abnormal morphology
  • abnormality
  • duplication
  • ploidy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microtubule cytoskeleton
  • spindle apparatus
  • Nucleus
  • centrosome
  • midbody
  • spindle pole
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Sac3d1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell division
  • spindle assembly
  • centrosome duplication

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • centrosome
  • cytoplasm
  • spindle
  • macromolecular complex

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.