Rxfp4 Gene Summary [Mouse]
Predicted to enable G protein-coupled peptide receptor activity. Acts upstream of or within positive regulation of feeding behavior. Predicted to be active in plasma membrane. Is expressed in alimentary system; genitourinary system; respiratory system; and thymus. Orthologous to human RXFP4 (relaxin family peptide/INSL5 receptor 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rxfp4 |
| Official Name | relaxin family peptide receptor 4 [Source:MGI Symbol;Acc:MGI:2182926] |
| Ensembl ID | ENSMUSG00000049741 |
| Bio databases IDs | |
| Aliases | relaxin family peptide receptor 4 |
| Synonyms | GPCR142, GPR100, relaxin family peptide/INSL5 receptor 4, relaxin family peptide receptor 4, RLN3R2, Rxfp4-ps1, RXFPR4, SALPR |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rxfp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- G-protein coupled receptor
- Cholecystokinin A receptor, N-terminal
- 7 transmembrane receptor (rhodopsin family)
- protein binding
- seven-transmembrane G protein-coupled receptor superfamily
Pathways
Biological processes and signaling networks where the Rxfp4 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cell surface
- cellular membrane
- sperm tail
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rxfp4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- neuropeptide signaling pathway
- positive regulation of feeding behavior
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- G-protein coupled peptide receptor activity
- protein binding