Tspan3 Gene Summary [Mouse]

Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including gonad; intestine; lung; sensory organ; and skeleton. Orthologous to human TSPAN3 (tetraspanin 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Processed Transcript
Official Symbol
Tspan3
Official Name
tetraspanin 3 [Source:MGI Symbol;Acc:MGI:1928098]
Ensembl ID
ENSMUSG00000032324
Bio databases IDs NCBI: 56434 Ensembl: ENSMUSG00000032324
Aliases tetraspanin 3
Synonyms 1700055K04Rik, Tetraspanin 3, TM4-A, TM4SF8
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tspan3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tetraspanin_LEL
  • Tetraspanin family

Pathways

Biological processes and signaling networks where the Tspan3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • chronic obstructive pulmonary disease
  • nonalcoholic steatohepatitis
  • coronary artery disease
regulated by
role in cell
  • proliferation
  • migration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tspan3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • extracellular vesicular exosome
  • plasma membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.