Swsap1 Gene Summary [Mouse]

Predicted to enable ATP hydrolysis activity and single-stranded DNA binding activity. Predicted to be involved in double-strand break repair via homologous recombination and protein stabilization. Predicted to be located in nucleus. Predicted to be part of Shu complex. Orthologous to human SWSAP1 (SWIM-type zinc finger 7 associated protein 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Swsap1
Official Name
SWIM type zinc finger 7 associated protein 1 [Source:MGI Symbol;Acc:MGI:1914212]
Ensembl ID
ENSMUSG00000051238
Bio databases IDs NCBI: 66962 Ensembl: ENSMUSG00000051238
Aliases SWIM type zinc finger 7 associated protein 1
Synonyms 2310047B19Rik, C19orf39, RGD1308026, SWIM-type zinc finger 7 associated protein 1, SWS1AP1, ZSWIM7AP1
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Swsap1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • single-stranded DNA binding
  • enzyme
  • protein binding
  • ATPase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • cutaneous melanoma
  • cutaneous melanoma cancer
regulated by
  • BCYRN1

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Swsap1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • double-strand break repair via homologous recombination
  • protein stabilization

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • Shu complex

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • protein binding
  • single-stranded DNA binding

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