Zdhhc19 Gene Summary [Mouse]
Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation; positive regulation of aggrephagy; and protein targeting to membrane. Predicted to be located in Golgi membrane and perinucleolar compartment. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC19 (zinc finger DHHC-type palmitoyltransferase 19). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zdhhc19 |
| Official Name | zinc finger, DHHC domain containing 19 [Source:MGI Symbol;Acc:MGI:2682948] |
| Ensembl ID | ENSMUSG00000052363 |
| Bio databases IDs | |
| Aliases | zinc finger, DHHC domain containing 19 |
| Synonyms | DHHC19, Gm1744, Gm616, RGD1560310, zinc finger, DHHC domain containing 19, zinc finger DHHC-type palmitoyltransferase 19 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zdhhc19 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein-cysteine S-palmitoleyltransferase
- DHHC palmitoyltransferase
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- Golgi membrane
- perinucleolar compartments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zdhhc19 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- peptidyl-L-cysteine S-palmitoylation
- protein targeting to membrane
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- Golgi membrane
- endoplasmic reticulum
- Golgi apparatus
Molecular Function
What the gene product does at the molecular level
- protein-cysteine S-palmitoleyltransferase activity