Trmt1l Gene Summary [Mouse]

Predicted to enable tRNA (guanine) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Acts upstream of or within adult locomotory behavior. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; hemolymphoid system gland; male reproductive gland or organ; nervous system; and respiratory system. Orthologous to human TRMT1L (tRNA methyltransferase 1 like). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Retained Intron
Official Symbol
Trmt1l
Official Name
tRNA methyltransferase 1 like [Source:MGI Symbol;Acc:MGI:1916185]
Ensembl ID
ENSMUSG00000053286
Bio databases IDs NCBI: 98685 Ensembl: ENSMUSG00000053286
Aliases tRNA methyltransferase 1 like
Synonyms 1190005F20Rik, bG120K12.3, C1orf25, MST070, MSTP070, RGD1307890, TRM1L, Trm1-like, tRNA methyltransferase 1L, tRNA methyltransferase 1-like
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trmt1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • N2,N2-dimethylguanosine tRNA methyltransferase
  • tRNA(guanine-26,N2-N2) methyltransferase
  • enzyme
  • protein binding
  • AdoMet_MTases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-small cell lung cancer
regulated by
  • aphidicolin
role in cell
  • processing in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trmt1l gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • metal ion binding
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

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