Trmt1l Gene Summary [Rat]
Predicted to enable tRNA (guanine) methyltransferase activity; tRNA binding activity; and zinc ion binding activity. Predicted to be involved in tRNA N2-guanine methylation. Predicted to act upstream of or within adult locomotory behavior. Predicted to be active in nucleus. Orthologous to human TRMT1L (tRNA methyltransferase 1 like). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Trmt1l |
| Official Name | tRNA methyltransferase 1-like [Source:RGD Symbol;Acc:1307890] |
| Ensembl ID | ENSRNOG00000002580 |
| Bio databases IDs | |
| Aliases | tRNA methyltransferase 1-like |
| Synonyms | 1190005F20Rik, bG120K12.3, C1orf25, MST070, MSTP070, RGD1307890, TRM1L, Trm1-like, tRNA methyltransferase 1L, tRNA methyltransferase 1-like |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Trmt1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- N2,N2-dimethylguanosine tRNA methyltransferase
- tRNA(guanine-26,N2-N2) methyltransferase
- enzyme
- protein binding
- AdoMet_MTases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Trmt1l gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- metal ion binding
- tRNA binding