Rpia Gene Summary [Mouse]
Enables ribose-5-phosphate isomerase activity. Involved in pentose-phosphate shunt. Is active in cytosol. Is expressed in alimentary system; cerebral cortex; heart; liver; and respiratory system. Orthologous to human RPIA (ribose 5-phosphate isomerase A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpia |
| Official Name | ribose 5-phosphate isomerase A [Source:MGI Symbol;Acc:MGI:103254] |
| Ensembl ID | ENSMUSG00000053604 |
| Bio databases IDs | |
| Aliases | ribose 5-phosphate isomerase A |
| Synonyms | ribose 5-phosphate isomerase A, RPI, Rpi1, RPIAD |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpia often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SugarP_isomerase
- Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
- ribose-5-phosphate isomerase
- monosaccharide binding
- enzyme
- protein binding
- carbohydrate binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpia gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pentose-phosphate shunt, non-oxidative branch
- pentose-phosphate shunt
- D-ribose metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- monosaccharide binding
- ribose-5-phosphate isomerase activity