Pm20d2 Gene Summary [Mouse]

Enables dipeptidase activity. Acts upstream of or within proteolysis and regulation of protein metabolic process. Predicted to be located in nucleoplasm. Orthologous to human PM20D2 (peptidase M20 domain containing 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Pm20d2
Official Name
peptidase M20 domain containing 2 [Source:MGI Symbol;Acc:MGI:2685270]
Ensembl ID
ENSMUSG00000054659
Bio databases IDs NCBI: 242377 Ensembl: ENSMUSG00000054659
Aliases peptidase M20 domain containing 2
Synonyms ACY1L2, Gm424, peptidase M20 domain containing 2
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pm20d2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Zinc peptidases M18, M20, M28, and M42
  • dipeptidase
  • Peptidase family M20/M25/M40
  • peptidase
  • protein binding
  • Peptidase dimerization domain
  • identical protein binding
  • amidohydrolase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • carnosine
  • gamma-aminobutyryl-ornithine
  • beta-alanyl-L-lysine
  • beta-alanyl-ornithine
  • gamma-aminobutyryl-lysine
  • homocarnosine
  • beta-alanyl-L-arginine
role in cell
  • synthesis in
  • accumulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Pm20d2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of protein metabolic process
  • proteolysis
  • folic acid catabolic process

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • carboxypeptidase activity
  • protein binding
  • dipeptidase activity
  • para-aminobenzoyl-glutamate hydrolase activity

Gene-Specific Assays for Results You Can Trust

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