PM20D2 Gene Summary [Human]
Enables dipeptidase activity and identical protein binding activity. Acts upstream of or within proteolysis and regulation of cellular protein metabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | PM20D2 |
| Official Name | peptidase M20 domain containing 2 [Source:HGNC Symbol;Acc:HGNC:21408] |
| Ensembl ID | ENSG00000146281 |
| Bio databases IDs | |
| Aliases | peptidase M20 domain containing 2, β-alanyl-lysine dipeptidase |
| Synonyms | ACY1L2, Gm424, peptidase M20 domain containing 2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human PM20D2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc peptidases M18, M20, M28, and M42
- dipeptidase
- Peptidase family M20/M25/M40
- peptidase
- protein binding
- Peptidase dimerization domain
- identical protein binding
- amidohydrolase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human PM20D2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of protein metabolic process
- proteolysis
- folic acid catabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- carboxypeptidase activity
- protein binding
- dipeptidase activity
- para-aminobenzoyl-glutamate hydrolase activity