Ap1s3

Predicted to enable clathrin adaptor activity. Predicted to be involved in protein targeting and vesicle-mediated transport. Predicted to be located in early endosome; lysosomal membrane; and trans-Golgi network membrane. Predicted to be part of AP-1 adaptor complex. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in bladder; embryo; renal cortex; urethra; and urinary system. Human ortholog(s) of this gene implicated in psoriasis 15. Orthologous to human AP1S3 (adaptor related protein complex 1 subunit sigma 3). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ap1s3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ap1s3 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ap1s3 gene, providing context for its role in the cell.