Kif13a Gene Summary [Mouse]
Enables microtubule motor activity. Involved in Golgi to plasma membrane protein transport and plus-end-directed vesicle transport along microtubule. Located in trans-Golgi network membrane. Is expressed in several structures, including 1st branchial arch; central nervous system; future brain; sensory organ; and tooth. Orthologous to human KIF13A (kinesin family member 13A). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kif13a |
| Official Name | kinesin family member 13A [Source:MGI Symbol;Acc:MGI:1098264] |
| Ensembl ID | ENSMUSG00000021375 |
| Bio databases IDs | |
| Aliases | kinesin family member 13A |
| Synonyms | 4930505I07Rik, bA500C11.2, kinesin family member 13A, mKIAA4109, RBKIN |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kif13a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kinesin protein 1B
- Myosin and Kinesin motor domain
- Forkhead associated domain
- protein binding
- microtubule motor protein
- Kinesin-associated
- forkhead associated (FHA) domain superfamily
- Kinesin motor, catalytic domain
- microtubule binding
- Kinesin protein
- FHA domain
- Kinesin motor domain
- tail domain
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- acute myeloid leukemia
- psoriasis
- chronic obstructive pulmonary disease
- colorectal cancer
role in cell
- migration
- growth
- maturation
- quantity
- cytokinesis
- motility
- organization
- cytokinesis in
- cargo loading in
- maturation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- membrane fraction
- perinuclear region
- centrosome
- Golgi Apparatus
- midbody
- trans Golgi network
- endosomal membrane
- cytoplasmic vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kif13a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- melanosome organization
- plus-end-directed vesicle transport along microtubule
- cytoskeleton-dependent intracellular transport
- regulation of cytokinesis
- cargo loading into vesicle
- Golgi to plasma membrane protein transport
- endosome to lysosome transport
- microtubule-based movement
- intracellular protein transport
Cellular Component
Where in the cell the gene product is active
- centrosome
- Golgi membrane
- kinesin complex
- endosome membrane
- midbody
- trans-Golgi network membrane
- microtubule
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- microtubule motor activity
- protein binding
- microtubule binding