Cnot10 Gene Summary [Mouse]
Predicted to be involved in mRNA catabolic process and negative regulation of translation. Predicted to be located in cytosol. Predicted to be part of CCR4-NOT complex. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and white fat. Orthologous to human CNOT10 (CCR4-NOT transcription complex subunit 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cnot10 |
| Official Name | CCR4-NOT transcription complex, subunit 10 [Source:MGI Symbol;Acc:MGI:1926143] |
| Ensembl ID | ENSMUSG00000056167 |
| Bio databases IDs | |
| Aliases | CCR4-NOT transcription complex, subunit 10 |
| Synonyms | 2600001P13RIK, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex, subunit 10 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cnot10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- tetratricopeptide repeat
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Cnot10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- gene silencing by RNA
- mRNA catabolic process
- negative regulation of translation
- nuclear-transcribed mRNA poly(A) tail shortening
Cellular Component
Where in the cell the gene product is active
- nucleus
- membrane
- cytosol
- CCR4-NOT complex
Molecular Function
What the gene product does at the molecular level
- protein binding