Rpl38 Gene Summary [Mouse]
A structural constituent of ribosome. Acts upstream of or within several processes, including 90S preribosome assembly; middle ear morphogenesis; and sensory perception of sound. Located in cytoplasm. Part of cytosolic large ribosomal subunit and eukaryotic 80S initiation complex. Is active in synapse. Is expressed in thymus primordium. Used to study otitis media. Orthologous to human RPL38 (ribosomal protein L38). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rpl38 |
| Official Name | ribosomal protein L38 [Source:MGI Symbol;Acc:MGI:1914921] |
| Ensembl ID | ENSMUSG00000057322 |
| Bio databases IDs | |
| Aliases | ribosomal protein L38 |
| Synonyms | 0610025G13RIK, eL38, L38, LOC688248, RBT, ribosomal protein L38, Ts, TSS |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpl38 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- structural constituent of ribosome
- protein binding
- Ribosomal L38e protein family
- RNA binding
Pathways
Biological processes and signaling networks where the Rpl38 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- cytosol
- synapse
- postsynaptic density
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpl38 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of translation
- sensory perception of sound
- skeletal system development
- 90S preribosome assembly
- ossification
- cytoplasmic translation
- ribonucleoprotein complex assembly
- middle ear morphogenesis
- translation
- axial mesoderm development
Cellular Component
Where in the cell the gene product is active
- postsynaptic density
- eukaryotic 80S initiation complex
- cytosolic ribosome
- focal adhesion
- cytoplasm
- cytosol
- cytosolic large ribosomal subunit
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- structural constituent of ribosome