Zfp422 Gene Summary [Mouse]
This gene encodes a putative C2H2 zinc finger transcription factor that may play a role in tooth development. A pseudogene related to this gene is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Details
| Type | Protein Coding |
| Official Symbol | Zfp422 |
| Official Name | zinc finger protein 422 [Source:MGI Symbol;Acc:MGI:1914505] |
| Ensembl ID | ENSMUSG00000059878 |
| Bio databases IDs | |
| Aliases | zinc finger protein 422 |
| Synonyms | 2900028O21Rik, HKR-T1, KOX15, Krox-25, Krox-25-2, KROX26, ZFP422, zinc finger protein 22, zinc finger protein 422, ZNF422 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Zfp422 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- zinc ion binding
- Zinc-finger double domain
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Zfp422 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- odontogenesis
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding
- sequence-specific DNA binding transcription factor activity
- protein binding