Zfp422 Gene Summary [Rat]
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human ZNF22 (zinc finger protein 22). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp422 |
| Official Name | zinc finger protein 422 [Source:RGD Symbol;Acc:620229] |
| Ensembl ID | ENSRNOG00000013379 |
| Bio databases IDs | |
| Aliases | zinc finger protein 422 |
| Synonyms | 2900028O21Rik, HKR-T1, KOX15, Krox-25, Krox-25-2, KROX26, ZFP422, zinc finger protein 22, zinc finger protein 422, ZNF422 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfp422 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- zinc ion binding
- Zinc-finger double domain
- protein binding
- DNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zfp422 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
- odontogenesis
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- zinc ion binding
- sequence-specific DNA binding transcription factor activity
- protein binding