Mcpt4 Gene Summary [Mouse]
Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within regulation of angiotensin levels in blood. Predicted to be active in extracellular space. Is expressed in lower jaw and upper jaw. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mcpt4 |
| Official Name | mast cell protease 4 [Source:MGI Symbol;Acc:MGI:96940] |
| Ensembl ID | ENSMUSG00000061068 |
| Bio databases IDs | |
| Aliases | mast cell protease 4 |
| Synonyms | LOC100365795, mast cell protease 1-like 1, mast cell protease 4, Mcp-4, Mcpt1, Mcpt1l1, MMCP-4, MMCP-4A, MMCP-4B, rMCP-1, rMCP-I |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mcpt4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Trypsin-like serine protease
- trypsin
- Tryp_SPc
- serine endopeptidase
- peptidase
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
- proteinuria
- blistering
- fibrosis
- tubulo-interstitial fibrosis
- astrocytosis
- bullous pemphigoid
- airway hyperresponsiveness
role in cell
- activation in
- apoptosis
- cellular infiltration by
- infiltration by
- morphology
- quantity
- hypertrophy
- recruitment
- function
- disruption
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- intracellular space