Fiz1 Gene Summary [Mouse]
Enables receptor tyrosine kinase binding activity. Acts upstream of or within positive regulation of protein phosphorylation. Located in chromatin; cytoplasm; and nucleus. Is expressed in several structures, including brain ventricular layer; early conceptus; genitourinary system; sensory organ; and tooth. Orthologous to human FIZ1 (FLT3 interacting zinc finger 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Fiz1 |
| Official Name | Flt3 interacting zinc finger protein 1 [Source:MGI Symbol;Acc:MGI:1344336] |
| Ensembl ID | ENSMUSG00000061374 |
| Bio databases IDs | |
| Aliases | Flt3 interacting zinc finger protein 1 |
| Synonyms | FLJ14768, FLT3-interacting zinc finger 1, Flt3 interacting zinc finger protein 1, mFLJ00416, RGD1306359, ZNF798 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Fiz1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- transcription regulator
- transcription co-activator
- receptor tyrosine kinase binding
- Zinc-finger double domain
- transcription factor binding
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- photoreceptor inner segments
- chromatin
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Fiz1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- positive regulation of protein phosphorylation
- positive regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
- chromatin
Molecular Function
What the gene product does at the molecular level
- transcription coactivator activity
- metal ion binding
- receptor tyrosine kinase binding