Ciao1

Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of MMXD complex and cytosolic [4Fe-4S] assembly targeting complex. Is expressed in several structures, including central nervous system; genitourinary system; liver; neural retina; and skin. Orthologous to human CIAO1 (cytosolic iron-sulfur assembly component 1). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ciao1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ciao1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ciao1 gene, providing context for its role in the cell.