CEP128 Gene Summary [Human]
Involved in protein localization. Located in centriole and spindle pole. Part of centriolar subdistal appendage. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | CEP128 |
| Official Name | centrosomal protein 128 [Source:HGNC Symbol;Acc:HGNC:20359] |
| Ensembl ID | ENSG00000100629 |
| Bio databases IDs | |
| Aliases | centrosomal protein 128 |
| Synonyms | 4930534B04Rik, 5430424K18Rik, AI449708, AI480494, C14orf145, C14orf61, centrosomal protein 128, E230024F20, LEDP/132 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CEP128 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- RIM-binding protein of the cytomatrix active zone
- chromosome segregation protein SMC, primarily archaeal type
- exonuclease SbcC
- Synaptonemal complex protein 1 (SCP-1)
- Growth-arrest specific micro-tubule binding
- helix-rich Mycoplasma protein
- Calcium binding and coiled-coil domain (CALCOCO1) like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- basal bodies
- centrosome
- Golgi Apparatus
- centriole
- spindle pole
- nuclear envelope
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CEP128 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein localization
- regulation of gene expression
Cellular Component
Where in the cell the gene product is active
- nuclear membrane
- centrosome
- centriole
- spindle pole
- Golgi apparatus