Lrmda Gene Summary [Mouse]

Predicted to be involved in melanocyte differentiation. Is expressed in embryo. Human ortholog(s) of this gene implicated in oculocutaneous albinism type VII. Orthologous to human LRMDA (leucine rich melanocyte differentiation associated). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lrmda
Official Name
leucine rich melanocyte differentiation associated [Source:MGI Symbol;Acc:MGI:1923883]
Ensembl ID
ENSMUSG00000063458
Bio databases IDs NCBI: 76633 Ensembl: ENSMUSG00000063458
Aliases leucine rich melanocyte differentiation associated
Synonyms 1700112E06Rik, 2700009F18Rik, C10orf11, CDA017, leucine rich melanocyte differentiation associated, LOC681383
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Lrmda often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • leucine-rich repeat
  • Leucine rich repeat
  • Leucine Rich repeats (2 copies)

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • metabolic syndrome X
  • insomnia
  • chronic obstructive pulmonary disease
  • cleft palate
  • cleft lip
  • refractive error
  • anorexia nervosa
  • alopecia
  • COVID-19
regulated by
role in cell
  • activation
  • differentiation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Lrmda gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • melanocyte differentiation