Jakmip1 Gene Summary [Mouse]
Enables kinesin binding activity. Predicted to be involved in cognition. Predicted to be located in membrane and microtubule cytoskeleton. Predicted to be part of ribonucleoprotein complex. Is expressed in cortical plate and embryo. Used to study autism spectrum disorder. Orthologous to human JAKMIP1 (janus kinase and microtubule interacting protein 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Jakmip1 |
| Official Name | janus kinase and microtubule interacting protein 1 [Source:MGI Symbol;Acc:MGI:1923321] |
| Ensembl ID | ENSMUSG00000063646 |
| Bio databases IDs | |
| Aliases | janus kinase and microtubule interacting protein 1 |
| Synonyms | 5830437M04Rik, C330021K24Rik, Gababrbp, JAMIP1, janus kinase and microtubule interacting protein 1, MARLIN1, Mgi:1923321 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Jakmip1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- chromosome segregation protein SMC, primarily archaeal type
- JAKMIP CC3 domain
- coiled-coil domain
- protein binding
- receptor binding
- kinesin binding
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- detergent-insoluble fractions
- membrane fraction
- microtubule cytoskeleton
- cellular membrane
- microtubules
- granules
- granular components
- neurites
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Jakmip1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cognition
- protein transport
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- membrane
- microtubule
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- GABA receptor binding
- kinase binding
- microtubule binding